Center of Experimental Morphology

Departamento de Anatomia - Faculdade de Medicina da Universidade do Porto

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Protective effects of chronic green tea consumption on dendritic trees during ageing

Research Area: Uncategorized Year: 2013
Type of Publication: Article
Pages: 6-9
Ageing is associated with oxidative stress-related biochemical alterations that cause progressive neuronal damage in the brain leading to deleterious morphological and behavioural modifications. On the other hand, catechins present in beverages such as green tea (GT) display strong antioxidant and anti-inflammatory properties. In Golgi-impregnated dentate granule cells of old rats we have analysed the structure of dendritic trees and the number of dendritic spines after a prolonged GT treatment. Our results demonstrate that the chronic consumption of GT during ageing protected neurons of the hippocampal formation, an important region involved in cognition, from age-associated detrimental morphological changes in dendritic trees, supporting the involvement of the GT catechins on such protection.

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